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The Sitcheran Lab

         at Texas A&M Health Science Center


Jung JU#, Ravi S# Lee DW,  McFadden K,  Kamradt ML, Toussaint LG, SitcheranR*NIK/MAP3K14 regulates mitochondrial dynamics and trafficking to promote cell invasion. Current Biology. 2016 Dec 19;26(24):3228-302.  doi:10.1016/j.cub.2016.10.009


Duran CL, Lee DW, Jiung JU, Ravi S, Pogue CB, Toussaint LG, Bayless KJ, Sitcheran R*. NIK regulates MT1-MMP activity and promotes glioma cell invasion independently of the canonical NF-κB pathwayOncogenesis. 2016 Jun 6;5(6):e231; doi:10.1038/oncsis.2016.39.

Cherry EM#, Lee DW#,  Jiung JU, Sitcheran R*. Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) promotes glioma cell invasion through induction of NF-κB-inducing kinase (NIK) and noncanonical NF-κB  signalingMolecular Cancer. 2015 Jan27; 14(1):9. DOI: 10.1186/s12943-014-0273-1. 

Lee DW#, Ramakrishnan D#, Valenta J, Parney IF, Bayless KJ, Sitcheran R*. The NF-κB RelB Protein Is an Oncogenic Driver of Mesenchymal Glioma. PLoS ONE 2013. 8(2): e57489. doi:10.1371/journal.pone.0057489.

Comb W, Cogswell P, Sitcheran R, Baldwin AS. IKK-Dependent, NF-κB-Independent Control of Expression of Key Autophagic Genes. 2010. Oncogene. Apr 7;30(14):1727-32.

O’Shaughnessy MJ, Bogtenhuber C, Sun K, Sitcheran R, Baldwin AS, Murphy WJ, Dang L, Jafee B, Palmer E, Serody JS, Blazar BR. (2009). Ex vivo inhibition of NF-κB signaling in alloreactive T cells prevents graft-versus-host disease. Amer. J. Transplantation. Mar;9(3):452-62.

Sitcheran R*, Comb WC, Cogswell PC, Baldwin AS*. Essential role for epidermal growth factor receptor in glutamate receptor signaling to NF-kappaB. Mol Cell Biol. (2008) Aug;28(16):5061-70. Epub 2008 Jun 9.

Sitcheran R, Gupta P, Fisher PB, Baldwin AS. Positive and negative regulation of EAAT2 by NF-kappaB: a role for N-myc in TNFalpha-controlled repression. EMBO J. (2005). Feb 9;24(3):510-20. Epub 2005 Jan 20.

Loercher A, Lee TL, Ricker JL, Howard A, Geoghegen J, Chen Z, Sunwoo JB, Sitcheran R, Chuang EY, Mitchell JB, Baldwin AS Jr, Van Waes C. Nuclear factor-kappaB is an important modulator of the altered gene expression profile and malignant phenotype in squamous cell carcinoma. Cancer Res. 2004 Sep 15;64(18):6511-23. 

Sitcheran R, Cogswell PC, Baldwin AS Jr. NF-kappaB mediates inhibition of mesenchymal cell differentiation through a posttranscriptional gene silencing mechanism. Genes Dev. 2003 Oct 1;17(19):2368-73.

# Co-first author

* Corresponding author

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